Lectures, case studies. 3 hours per day during Winter Session. The interaction between genes and environmental and/or occupational exposures plays a major role in disease development. This course will focus on the underlying science of gene-exposure interactions and will use examples of such interactions and their health consequences. Gene-environment interactions will be discussed using an epidemiologic approach to address how genetic polymorphisms can influence susceptibility to disease. This course will enable students to understand and apply findings of genetic association studies and will consist of detailed evaluation of specific examples of gene-exposure interactions and their health consequences, as well as their social implications.